Health Minister Norman Lamb has told ITV Daybreak that there has to be a proper process to ensure that people who fail in the health service are held to account.
He added: It was "utterly unacceptable what happened", and that we simply cannot have "rewards for failure".
The families of victims are calling for the resignation of NHS chief Sir David Nicholson, who was chief executive of the West Midlands Strategic Health Authority (WMSHA) between August 2005 and April 2006.
A public inquiry has blamed a failure 'at every level' of the NHS for the abuses at Stafford Hospital that resulted in hundreds of deaths.
The chair of the inquiry into Mid Staffordshire NHS made 290 recommendations to prevent the 'disaster' of Stafford Hospital occurring again.
Managers at Stafford Hospital accept that there were problems on some of the wards. But they say it's now one of the best in the country.