As part of the ITV1 special 'From the Heart' X Factor winner Alexandra Burke described how her family kept her mother's illness from her during the 2008 final of the X Factor.
Alexandra's mother Melissa needs a kidney transplant, and spends 8 hours a day on a dialysis machine, as she waits for one.
The severe shortage of Black, Asian and Minority Ethnic organ donors mean that donors from these communities have to wait three times longer to get the transplant they need.
Vincenzo has been transformed from a patient so sick he could not wash his face to a man who strides confidently with a gleam in his eye.
A look at organ donation rates around the world and how the UK compares.
In a one hour special the Tonight programme investigates the lives of the 10,000 Brits on waiting lists for an organ transplant.