As a global sports icon Oscar Pistorius has various sponsorship deals, including one with sports giant Nike, thought to be worth $2 million a year.
South Africa's M-Net cable TV channel said it was pulling adverts featuring Pistorius off-air immediately.
Earlier, a Nike spokesman in London said before hearing of the murder charge that the company was "saddened by the news, but we have no further comment to make at this stage".
Icelandic prosthetics manufacturer Ossur said:
I can only say that our thoughts and prayers are with Oscar and the families involved in the tragedy. It is completely premature to discuss or speculate on our business relationship with him.
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The mother of one of the Manchester attack victims has told of the distressing moment she found her daughter being treated after the attack.
Marjorie and Michael Cawdery, both 83, are understood to have been stabbed to death in a killing their family called "incomprehensible".
Detectives have launched a murder investigation following the shooting in Brent, north west London on Friday night.