NHS boss Sir David Nicholson has said health service leaders need to "absorb the criticism" in the wake of a report into the Stafford Hospital scandal.
Mr Nicholson praised recommended changes to the NHS in the Francis Report as "radical" and said "getting the right culture" in the health service was vital, adding: "Standards are so, so important."
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Staff at the hospital treating critically-ill baby Charlie Gard have received "shocking" abuse including death threats over the case.
The actor, best known for his role as the dad in Home Alone, was found dead on Friday in his hotel room in Palo Alto, California.