Secretary of State John Kerry said the US will channel $60 million in aid to Syrian groups the US chooses, which is a clear message that jihadi groups must be excluded from the aid.
Although the US aid is "non lethal", this is the biggest package and strongest back-up yet given so far by the US to Syrian rebels.
Mr Kerry said "no people should live in fear of their so called leaders" and "we must meet the moment."
US backing of the Syria rebels today is at its most public, financial, open and morally clear.
More top news
Craig Johnson, 25, was driving with partner Julie Douglas and their one-year-old daughter Maisie when the rock was hurled at them.
A terminally ill five-year-old boy led out the England team at Wembley with his "best friend" Jermain Defoe.
It comes as the country faces a major migrant crisis with more than 62,000 stranded including outside the port of Piraeus.