Speaking in Westminster following the Health Select Committee, Julie Bailey, who set up the Cure The NHS campaign group after her mother Bella died at Stafford Hospital in 2007, said Sir David's evidence was "shameful" and "embarrassing".
"That man is an absolute disgrace," she said.
Asked about suggestions that he would stay in post to lead reform of the NHS, she replied: "I think it's just laughable. He is desperate to carry on in his job."
She added: "We need to get rid of him. Nothing will change. He is part of the problem, not the solution."
More top news
Doctors have recommend Peter Sutcliffe be moved to high security prison, but the final decision will be taken by the justice secretary.
Last minute suspension of strike action has meant thousands of cancelled procedures will still not go ahead.
Children in the North and the Midlands are less likely to get a good secondary education than those in the South, schools inspector to say.