Asked what changes were required to implement the recommendations of the Francis Report on Mid Staffordshire Hospital, Sir David Nicholson said: "This is a significant change programme for the NHS from literally top to bottom.
"It's from setting out basic standards that patients and everyone can understand and assessing and inspecting again against them."
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A judge ruled the boy may be allowed home from Alder Hey Children’s Hospital, but will not be allowed to go to Rome for further treatment.
Alek Minassian, 25, has been charged with first degree murder.
The president, meanwhile, thanked the French leader for his “steadfast partnership” in the recent missile strike in Syria.