The Deputy Prime Minister will hail the by-election victory in Eastleigh as proof that the Lib Dems can succeed as a party of government.
He will also dismiss the "myth" that being in coalition has undermined their identity or ability to fight the Conservatives.
The rallying cry comes in a keynote speech to the Lib Dem spring conference in Brighton.
The leadership has been eager to use the gathering to move on from damaging allegations of sexual harassment by Lord Rennard - which he denies - and the conviction of former Cabinet minister Chris Huhne.
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The mayor of Paris has called for a black feminist festival in the French capital to be banned because it "prohibited white people".
More than 200 drivers a day were caught using their mobile phones illegally in the wake of a major crackdown on the practice.
Tougher sentences will be handed out to perpetrators of domestic violence against children under plans being set out by the Conservatives.