Hospital staff, paramedics and renal patients in North Wales have been driven to hospitals in 4x4 vehicles to negotiate the treacherous roads.
Red Cross volunteers have helped more than 70 people in the Wrexham and Flintshire areas so far, starting at 5am this morning.
David Hallows, service manager for emergency response for the Red Cross in North Wales, said: "It's great to know that our 4x4 capability can be of such vital use to medical staff in getting them through these tough weather conditions ...
"Snowy and icy weather such as this can cause huge problems for people, especially those living in rural areas.
"Driving conditions are particularly bad but our volunteers are all highly trained and happy to help."
The wintry conditions are now expected to last well into April with this month on track to become the coldest March since 1962.
A group of students from Wolverhampton who were stranded in extreme snow in Scotland for more than three days tell their story of survival.
Cold weather can pose a real health risk to older and disabled people, but everyone can gain from preparing their homes for the cold.