East Midlands Ambulance Service has confirmed reports of a crash between a lorry and a car in Grimsby this afternoon.
It is being reported that five people from the same family were killed in the head-on crash with an articulated lorry owned by New Century Foods of Scunthorpe.
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The incident is not believed to be terror-related, British Transport Police said.
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A small number of people were treated at Southgate Tube station, British Transport Police said.