Police said that the most serious incident in the scuffles following the derby match involved Newcastle fans in the city's Central Station "attempting to confront Sunderland supporters".
The fans were reportedly intercepted by officers from British Transport Police, resulting in three injuries to police officers.
Chief Superintendent Steve Neill of Northumbria Police said:
The vast majority of fans were well behaved today and enjoyed the Tyne Wear derby for the great occasion that it is.
Disappointingly, there was some disorder involving what appear to be
Newcastle United supporters following the match in the city centre,
including an incident at Central Station.
Disruptive behaviour of any kind is not tolerated, enquiries will take place into these incidents and action will be taken against all those involved.
A football fan who was filmed attempting to punch a police horse has told ITV News that he is ashamed of his actions.
A police horse seen being punched by a football fan is "safe and well" this morning, its police force said.