The Mayor of Reims Adeline Hazan has told the French news agency BFM TV that at least "two people were killed" in the accident at a four storey block of flats in the city.
Initial reports on local French media suggest the explosion may have been caused by a gas leak.
More top news
Particles in Pluto's haze create a stunning blue tinge around the dwarf planet in an image captured by the New Horizons space mission.
The world’s coral reefs are struggling. Scientists have declared that reefs across the world are facing a “global bleaching event”.
Some of us might be turning the heating on this week as a wind chill and low temperatures sneak in.