The Mayor of Reims Adeline Hazan has told the French news agency BFM TV that at least "two people were killed" in the accident at a four storey block of flats in the city.
Initial reports on local French media suggest the explosion may have been caused by a gas leak.
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The forecast is generally calm, quiet and dry as an area of cloud gives way to the south east and moves off to the near continent.
Artists have retold the stories of "imponderable brutality and evil" in works created to remember the Holocaust.
ITV News joins 85-year-old Holocaust survivor Zigi Shipper on his emotional return to the Auschwitz death camp.