In a statement, the Prime Minister of the Czech Republic Petr Necas said he was "deeply hit by the tragedy of the gas explosion", the Associated Press reports.
It is not certain what caused the blast in Divadelni Street in the central Prague but it was likely to be a natural gas explosion, police spokesman Tomas Hulan said.
More top news
The Chancellor will present his Autumn Statement and Spending Review to the House of Commons on Wednesday.
The shocking video of Laquan McDonald being killed brings the debate about racism in the US criminal justice system centre stage once more.
A video of a white police officer shooting dead a black teenager has been released by authorities in Chicago.