In a statement, the Prime Minister of the Czech Republic Petr Necas said he was "deeply hit by the tragedy of the gas explosion", the Associated Press reports.
It is not certain what caused the blast in Divadelni Street in the central Prague but it was likely to be a natural gas explosion, police spokesman Tomas Hulan said.
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The rain band will soon be clearing eastwards, but more showers will be affecting parts of the UK this afternoon.
David Cameron will stand down as Conservative leader ahead of the general election expected in 2020, Iain Duncan Smith said.
Delegates at the SNP spring conference have backed a move to allow all-female shortlists in the Scottish Parliament election next year.