There are no immediate reports of injuries relating to the explosions and fire in Belper, the Derby Telegraph reports citing local emergency services.
It also reported that people in the area are being advised to stay indoors to avoid breathing the air around the factory.
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The practice of sending mental health patients far away from friends and family for care has become endemic in the NHS, it has been warned.
Despite the use of combustible cladding in tower blocks, ministers were advised that regulations were tough enough, ITV News has learnt.
A milder night across the north than last night, with rain sneaking into southern Scotland from Northern Ireland.