David Cameron will today raise the prospect of using next month's G8 summit in Northern Ireland to launch negotiations for an EU-US trade deal.
Writing in the Wall Street Journal, Mr Cameron said:
When times are tough, some want to put the barriers up, to look inwards, and to protect themselves from the world.
But Britain and America stand for a better way. We have a precious opportunity to transform the global economy - not by less openness and less free trade, but by more. And we must do everything possible to seize it.
Trade is not a zero sum game where one nation's success is another's failure. Trade makes the cake bigger so everyone can benefit. Take the free trade area between Europe and the US on which we hope to launch negotiations when President Obama is in Northern Ireland for the G8 next month.
More top news
Six were wounded, two seriously, after an ultra-Orthodox man stabbed several people at Jerusalem's annual Gay Pride march.
Video shows inside the bin lorry in the immediate aftermath of the Glasgow city centre crash that killed six people days before Christmas.
A woman who underwent a keyhole hysterectomy woke up to find two of her teeth had gone missing.