David Cameron will today raise the prospect of using next month's G8 summit in Northern Ireland to launch negotiations for an EU-US trade deal.
Writing in the Wall Street Journal, Mr Cameron said:
When times are tough, some want to put the barriers up, to look inwards, and to protect themselves from the world.
But Britain and America stand for a better way. We have a precious opportunity to transform the global economy - not by less openness and less free trade, but by more. And we must do everything possible to seize it.
Trade is not a zero sum game where one nation's success is another's failure. Trade makes the cake bigger so everyone can benefit. Take the free trade area between Europe and the US on which we hope to launch negotiations when President Obama is in Northern Ireland for the G8 next month.
More top news
Five Britons have died after the car they were in plunged more than 80 feet from a bridge into a Swedish canal.
The Church of England has defended sending "prayers" on Twitter to The God Delusion author Richard Dawkins following his recent stroke.
Barack Obama and his wife Michelle have exchanged Valentine's Day messages on the The Ellen DeGeneres Show.