– Shadow Foreign Secretary Douglas Alexander
This vote is a further devastating blow to the Prime Minister's authority.
It demonstrates that David Cameron has managed to turn a Europe issue into a leadership issue.
This is a Prime Minister who has lost control of the agenda and tonight lost control of his Party.
David Cameron’s backbenchers have shown they simply won’t give up until he gives in.
The real risk is that he spends the coming month trying to get his party back in line, instead of focusing on getting our economy back on track.
The Lib Dem Business Secretary Vince Cable has criticised Tory backbenchers' moves for an EU referendum Bill, as "just reopening a Pandora's box which potentially is not only damaging to them as a party, but it is damaging to the country."