Asked for David Cameron's response to Sir David Nicholson's retirement and assessment of his record, the Prime Minister's official spokesman said: "He agrees with the Secretary of State for Health."
Mr Cameron's view of Sir David was "unchanged" since the PM responded to the Francis report on Mid-Staffordshire, said the spokesman.
He said he was not aware of ministers discussing the NHS chief's departure with Sir David in advance, adding: "It is his decision to retire."
More top news
Travellers hoping to get away for the Easter weekend are being warned of potentially serious problems on the road and rail networks.
Left-footed footballs, backwards web searches, police camels and an eco-friendly Jeremy Clarkson are among today's traditional tall tales.
There was an "alarming" increase in the number of death sentences issued around the world last year, Amnesty International has said.