The Deputy Prime Minister will say that Tory backbenchers are "consumed by game playing" after a week dominated by revolts over Europe and gay marriage.
He will however dismiss talks of a an early break-up between the Conservatives and Liberal Democrats, during a speech in Westminster.
Speculation over the coalition's future was fuelled this weekend when the Prime Minister raised in an interview the prospect of governing alone.
Mr Cameron told Total Politics magazine that despite some "frustrations", the coalition remained the best way to get things done.
"But if that wasn't the case then we'd have to face the new circumstances in whatever way we should,' he added.
More top news
The Metropolitan Police is to pay over £400,000 in compensation to a woman who had a child with an undercover officer.
Local councils want ban on term time holidays scrapped because it is too rigid.
It will be a wet start tomorrow for many but things are looking up for the afternoon.