Ms Eleanor Gray QC for Ashworth Hospital is questioning Dr Grounds on the reasons for Ian Brady's isolation at the hospital - she has suggested he is alone much of the time "because he is afraid of other [patients]".
Dr Grounds argues that Brady's behaviour resulted from contempt for other people; indifference; a lack of interest in others; and a sense of superiority.
"He is not a man who is fearful of others. Far from it," he said.
But Ms Gray referred to Brady's refusal to leave his room, and a reason he gave for this; a fear of his fellow-patients. Brady is recorded as saying: "...in these penal s***holes, any sign of weakness and they will jump you".
She says in addition Brady's general behaviour towards staff shows signs of paranoia and suspicion. "This is a grossly abnormal man who has been crippled by the disorders which he suffers".
More top news
A man with 62 penalty points on his licence is among thousands of motorists allowed to drive despite exceeding the limit warranting a ban.
Storm Doris is set to bring severe weather across much of the UK on Thursday as heavy rain and strong winds push in from the west.
President Trump has scrapped protections for transgender students that had allowed them to use bathrooms matching their gender identity.