Welsh health minister Mark Drakeford has argued that a new scheme that assumes consent for organ donation will increase the number of organs available for transplant.
He highlighted the fact that surveys have shown that a majority of Welsh people wish to be a donor.
Deemed consent will bring about a cultural shift in the way donation proceeds in Wales.
It will alter the nature of some of the most difficult conversations that any family might face, and it will help to ensure that the wishes of that substantial majority of Welsh citizens who say, in survey after survey, that they would wish to be a donor, are put into practice in those very rare and special circumstances when donation is possible.
The Welsh Assembly has voted for a change in the law to try and save the lives of those who die while they wait for a transplant organ.
As Wales votes on changes to organ donation, ITV News speaks to those for and against the changes.