Detective Chief Inspector Andy Redwood, head of the investigation into Madeleine McCann's disappearance, has said that they want to talk to 38 people from across Europe - including 12 UK nationals - in connection with they inquiry.
The missing girl's parents Gerry and Kate are not among the people of interest.
Police believe Madeleine could still be alive, and they have drawn up a list of 38 people - 12 of them British - who they want to speak to.
What happened to Madeleine? It is likely only one person knows the answer, and finding that person is the focus of a British investigation.
The Met Police said there are 38 people of interest in the Madeleine McCann case. Here is a timeline of the key events in her disappearance.