The Save Trafford General campaign said the closure of its A&E department is "tearing the heart out of the hospital".
Matthew Finnegan, the campaign's chairman, said the future of the hospital - widely considered to be the birthplace of the NHS - is now "in real danger".
Mr Finnegan said: "These decisions can't just be made by clinicians - they have got to listen to what local people say. And people want an A&E, it's not an unreasonable request.
"Local people will be appalled and disgusted that they have not been listened to."
More top news
The jailing of the British sailor - who was caught "red handed" - came as it emerged he is also wanted in connection with a murder in Spain.
A pregnant Brazilian woman who faced deportation is allowed to stay in Britain after a Home Office U-turn over Zika virus fears.
The off-duty police officer has been hailed after catching a brazen thief while out catching some rays with a friend in a Stockholm park.