Marathon world record-holder Paula Radcliffe will run the first event to be staged at London's Olympic Stadium since the 2012 Games later today.
Radcliffe, who was unable to compete at the London Olympics due to injury, will join a host of sporting stars including Olympic gold medallists Sir Chris Hoy and Victoria Pendleton, who are more used to cycling than running.
They will be among the 12,500 people taking part in the five-mile (eight-kilometre) National Lottery Anniversary Run, in which competitors will complete the final 328 yards (300m) on the Olympic Stadium's track.
Radcliffe has predicted the event would "recapture the spirit of the London 2012".
More top news
Tougher punishments for "barbaric" dog fighting are needed, according to a report which has found dogs are being trained to fight daily.
The Foreign Office should relax travel advice on Tunisia, the country's ambassador has said, after UK tourism to the country plummeted 90%.
Family holidays to Europe could rise by an average of £230 if Britain leaves the EU, the prime minister is warning.