The world's first test-tube baby has paid tribute to the fertility pioneers who gave her and millions of others life as she celebrates her 35th birthday.
Louise Brown's birth attracted controversy, with religious leaders expressing concern over the use of artificial intervention and some raising fears that science was creating "Frankenbabies" who could experience medical difficulties later in life.
There are now thought to be more than 5.5 million IVF babies worldwide and, as she prepared to celebrate her birthday with a private family meal, Mrs Brown said she hoped the public could now see the benefits of the breakthrough.
"When I was born they all said it shouldn't be done and that it was messing with God and nature but it worked and obviously it was meant to be," she added.
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