People are reported to be injured following a "serious collision" on the M25 in Surrey.
Six ambulances and four fire engines are at the scene of the accident between junctions 10 and 11, in which two people are believed to have suffered "serious injuries".
Surrey Police said the clockwise carriageway is expected to remain closed "for some time".
More top news
A 43rd generation direct descendant of the Prophet Muhammad, the Prince has vowed to clean up Fifa's act.
So-called legal highs are set to be banned en masse. But what are they, and why is this drastic move necessary?
The Swiss 79-year-old joined Fifa in 1975, with his reign as president starting in 1998. But who is he?