As many as one in 40 babies is born with a birth defect in England and Wales, according to the most comprehensive study of the issue to date.
The most common anomalies are congenital heart defects, which affect at least six in every 1,000 babies.
Those suffering heart problems can require major surgery, and around 6 percent of babies with a heart defect die before their first birthday.
The report, by researchers at Queen Mary University of London in conjunction with theBritish Isles Network of Congenital Anomaly Registers, collated data from six regional registers, giving a national coverage of 36% of all births.
Researchers then provided estimates to flesh out the other regions of England and Wales.
More top news
The fall in the pound has not put British people off of going on holiday, with sales of the euro and the dollar up.
The 75-year-old comic book character has been named UN ambassador for the empowerment of women and girls.
The women have gone straight to the top of the charts with their new song, Shout Out To My Ex.