Deputy Prime Minister Nick Clegg said the Government must ensure abused children like Daniel Pelka "do not fall in between the cracks of the system again".
Mr Clegg told ITV News it was "absolutely heartbreaking" that Daniel had been neglected and abused "in the most unimaginable way".
"The whole nation was shocked to our core when we saw what happened to this little poor boy," he added.
Opportunities to protect Daniel Pelka, who was beaten to death by his mother and stepfather, 'were missed' a serious case has revealed.
Daniel Pelka's Serious Case Review is strong on what went wrong, but weak on explaining why it was allowed to happen.