Nick Bonnie, 30, collapsed at a nightclub in Manchester in the early hours of Saturday.
Mr Cameron said: "This is a tragic death. We've seen too many of these".
When asked if the Government has a grip on its drugs policy, he said: "The focus of Government has quite rightly been on education...and treatment".
He added that he disagreed with the Chief Constable of Durham's call for some drugs to be decriminalised as "it would make them more available and lead to more problems".
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A four-year-old boy has died after being hit by a car outside a medical centre in Leeds.
The McCanns said they will do "whatever it takes for as long as it takes" to find their daughter, ten years after her disappearance.
The US President has marked his first 100 days in the White House by speaking at a campaign-style rally in Pennsylvania.