The McCanns' pain over the disappearance of their daughter was "multiplied 100 times" by a book by a former Portuguese police chief, a court has heard.
Gerry McCann's sister Trish Cameron said he and wife Kate had been "demonised" and "vilified" by the disappearance of Madeleine and claims that they were somehow involved.
She was speaking at the trial of former police chief Goncalo Amaral whose book, The Truth Of The Lie, suggested the McCann's hid their daughter's body after she died in an accident and faked an abduction.
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A total of 8,648 sailors died during the largest naval engagement during the First World War, which marks its centenary on Tuesday.
The figures by the Global Slavery Index are a third higher than previously thought.
Sara Di Pietrantonio, 22, died in Rome on Sunday.