The McCanns' pain over the disappearance of their daughter was "multiplied 100 times" by a book by a former Portuguese police chief, a court has heard.
Gerry McCann's sister Trish Cameron said he and wife Kate had been "demonised" and "vilified" by the disappearance of Madeleine and claims that they were somehow involved.
She was speaking at the trial of former police chief Goncalo Amaral whose book, The Truth Of The Lie, suggested the McCann's hid their daughter's body after she died in an accident and faked an abduction.
More top news
Taking more than the recommended daily amount of over-the-counter vitamins may increase the risk of cancer and heart disease by up to 20%.
Which? put in a 'super-complaint' after finding firms exaggerate discounts with dodgy multi-buys, shrinking products and baffling offers.
The Queen celebrates her 89th birthday today - but will she get to share it with her new great-grandchild?