An eight-year-old and two others were killed when gunmen on a motorcycle fired at wedding guests outside a Coptic Christian church in a Cairo suburb, state news agency MENA reported.
The masked assailants shot randomly at guests as they left the church, security sources said.
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"Africa is very important for the United States."
The incident happened at around 8pm local time on Thursday evening.
The Foreign Secretary said "good connections" were important, and suggested the Channel Tunnel might simply be "a first step."