Officers have said that they will travel regularly to Portugal as part of the UK investigation, following a meeting with Portuguese police, the Met Police said in a statement.
Assistance Commander Mark Rowley, specialist crime and operations, said: "The meeting was very positive, and we and the Policia Judiciara have a shared determination to do everything possible to discover what happened to Madeleine.
"Colleagues in Portugal fully shared with us the developments in their review, and the fact that they were taking the significant step of applying for the investigation to be formally reopened.
"From the near future, MPS detectives from Operation Grange will travel regularly to Portugal under the terms of the ILOR in relation to the UK investigation."
More top news
Judge Mindy Glazer was not expecting to be reunited with "the nicest kid in middle school" when Arthur Booth appeared in her court.
The WikiLeaks founder has been living in the Ecuadorian embassy in London for three years but claims his life is in danger.
Small shops in some parts of Greece are in danger of running out of coins and small change as cash reserves in the country begin to run low.