Every person aged 75 and over will be assigned a GP in a bid to make sure their care is co-ordinated, according to new contracts with the Government doctors have agreed to.
There are also changes to out-of-hours care - GPs will take on more responsibility and are expected to monitor the quality of their local service.
Both GPs and the Government hope the new deal will introduce an "enhanced service" for patients with complex health needs so they are not unnecessarily admitted to hospital or A&E.
The British Medical Association (BMA), which negotiated for doctors, said the changes would cut unnecessary targets, reduce bureaucratic box-ticking and give doctors more time to focus on the needs of their patients.
Dr Chaand Nagpaul, chair of the BMA's GP committee, said: "We have negotiated changes that will encourage GPs to provide more personalised care for vulnerable patients at risk of hospital admission, with improved access and other measures to better co-ordinate their care."