Former world champion David Haye underwent surgery on Thursday to reconstruct his right shoulder and has been told to "seriously consider ending his boxing career", Hayemaker Boxing said.
The Londoner has pulled out of his rescheduled February 8 fight with domestic rival Tyson Fury and looks set to end his career permanently after an unsuccessful operation last week.
"It's a crushing blow for me," he said. "I had big plans for next year and the ultimate goal was to win back the world heavyweight title, something my amazing fans deserve.
"What I didn't anticipate was that this year would be the unluckiest of my career and that a number of injuries would disrupt my plans so much.
"Perhaps it just wasn't meant to be. The boxing gods keep hinting that maybe enough is enough and that it's time to finally hang up my gloves."
More top news
A grandmother says she was outraged after her grandson was segregated from his classmates by a cardboard screen - for being one minute late.
Leaked documents have revealed the first known picture of Mohammed Emwazi - named as IS militant Jihadi John - as a student in London.
With March just around the corner it's looking like this winter will be the sunniest on record (data goes back to 1929).