The Metropolitan Transportation Authority said four or five carriages on the seven-carriages derailed close to the Spuyten Duyvil station in the Bronx, New York.
None of the cars entered the Hudson or Harlem rivers, which are adjacent.
Early reports indicate that four people have died and a further 48 are injured. This figure is expected to change.
More top news
Despite overcast weather a large crowd joined veterans and gathered around Dunkirk's memorial square to pay their respects.
A German 65-year-old teacher from Berlin has given birth to quadruplets after a pregnancy that was widely criticised because of her age.
Although there are bright skies for many as we start the bank holiday, more central, eastern and south eastern regions will be cloudy.