The Los Angeles County Sheriff's department has told the Associated Press that deputies found a car engulfed in flames, thought to be of actor Paul Walker's when they responded to a report of a collision in the community of Valencia in California.
Two people who were found in the car were pronounced dead at the scene.
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The entertainer, 65, brought the legal action against Essex police over a wrongful arrest which he says destroyed his career.
The Holby City star, who had been visiting Barcelona, detailed the events of the attack on Twitter as they unfolded.
Searches are continuing for victims, with around 600 people still missing and 3,000 left homeless after the disaster.