Two signed works of art by Damien Hirst were taken from an upmarket gallery after a suspect stormed the building in Blenheim Crescent, Notting Hill, London, between 3am and 3.30am on Monday.
The burglar entered the gallery by forcing open the front doors and drove the items away in a dark-coloured hatchback-type vehicle towards Ladbroke Grove, the Metropolitan Police said.
The stolen pieces feature multi-coloured dots - the larger work is entitled Pyronin Y, which was created in 2005 and worth £15,000 and the other is called Oleoylsarcosine, which is valued at £18,000.
Detective Sergeant Jon Lightfoot, from Kensington and Chelsea Borough, said: "It appears the suspect has specifically targeted the two pieces.
"The items would have been visible in the back of the car and we are appealing for any witnesses or anyone with information to please come forward."
More top news
Some trusts are not charging overseas patients despite them not being entitled to free treatment, a new report has revealed.
The vice presidential candidate was travelling with his wife, daughter and several campaign advisers, but no one was injured.
They deny a 'sweetheart deal' - but a senior source told ITV News the government promised to support such firms in the event of Brexit.