Two signed works of art by Damien Hirst were taken from an upmarket gallery after a suspect stormed the building in Blenheim Crescent, Notting Hill, London, between 3am and 3.30am on Monday.
The burglar entered the gallery by forcing open the front doors and drove the items away in a dark-coloured hatchback-type vehicle towards Ladbroke Grove, the Metropolitan Police said.
The stolen pieces feature multi-coloured dots - the larger work is entitled Pyronin Y, which was created in 2005 and worth £15,000 and the other is called Oleoylsarcosine, which is valued at £18,000.
Detective Sergeant Jon Lightfoot, from Kensington and Chelsea Borough, said: "It appears the suspect has specifically targeted the two pieces.
"The items would have been visible in the back of the car and we are appealing for any witnesses or anyone with information to please come forward."
More top news
A Manchester couple who funded their lavish globetrotting lifestyle by defrauding the NHS of up to £1 million have been jailed.
Disappointing grey skies, with a lot of cloud cover for most of the UK, but it will remain mainly mild for the time of year.
The cricketing landscape has changed following the tragic death of Australia batsman Phil Hughes, writes Mark Austin.