Icy air and gusting winds are expected to bring temperatures down as low as -50C in parts of the US with forecasters warning the Arctic grip could be life threatening.
The "polar vortex" - a rotating pool of cold, dense air - has brought the coldest weather in 20 years to the Mid-West.
ITV News' Lewis Vaughan-Jones reports from a nation bracing itself for the bitterest of weather:
As much of the US experiences a dangerous and severe cold spell, does the UK have anything to worry about?
As the US battles sub-zero temperatures, ITV News Washington correspondent Robert Moore illustrates just how cold it is in Minnesota.
Leaders across America are urging residents to stay in their homes as "polar vortex" batters the east coast after snowstorm Hercules.