The first pint has been bought at the Hope and Champion, a Wetherspoons pub located at the M40 services in Beaconsfield.
The controversial pub is Britain's first at a motorway service station, and will be open from 4am to 1am seven days a week.
More top news
British Bankers' Association head Anthony Browne warned that some banks could be moving abroad within weeks due to Brexit uncertainty.
Labour said its plan would mean grieving families would not have to pay for either a burial plot or cremation for a child aged under 16.
The children are among around 70 new young arrivals to arrive in Britain under the landmark Dubs amendment.