We showed that suppressing this gene reduced the spread of cancer by more than 80%.
Our next goal was to then find a way to suppress Bcl3 pharmacologically. Despite great improvements in therapy of early stage breast cancer, the current therapeutic options for patients with late stage metastatic disease are limited.
There is therefore a clear unmet clinical need to identify new drugs to reverse or at least to slow down disease progression.
More top news
Villarrica - one of Chile's most active volcanoes - has erupted, forcing the evacuation of nearby communities.
Footage showing the "truly shocking" moment a teenager was stabbed to death as he rode his bike with friends has been released.
Drinking three to five cups of coffee a day could reduce the risk of clogged arteries and thus heart attacks, a study has found.