It is unknown whether Amanda Knox and Raffaele Sollecito will appeal their murder convictions, or whether Knox could be extradited from the US to Italy.
A potential international legal battle is further complicated by US double jeopardy law which prevents defendants being tried twice for the same crime.
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The two brothers were aged 10 and 11 when they tortured two boys in Edlington, south Yorkshire, in 2009 in a case that shocked Britain.