Meredith Kercher's sister Stephanie and brother Lyle have spoken to the media after Amanda Knox and Raffaele Sollecito have had their guilty verdicts for the murder of the British student reinstated by judges.
They said that they are "still on the journey to the truth" and that America "should extradite" Knox.
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The star - who played Miranda Hobbes in the hit New York-set show - posted a message on Twitter announcing her run.
Another cold night to come before temperatures slowly start to recover throughout the coming week.
The opioid epidemic is so extreme in the US city of Manchester, that the drugs are killing almost 100 of the 100,000 residents each year.