British actor John Hurt, who starred alongside Philip Seymour Hoffman in the 2003 film Owning Mahowny, has said the news of the actor's death had hit him "very hard".
He told the BBC: "He was a great actor, a great member of the film and theatre community. An extraordinary talent, directorially as well as an actor. He'll be greatly missed".
A variation 100 time more potent than heroin - laced with the painkiller Fentanyl - is causing a spike in deaths on the US East Coast.
Philip Seymour Hoffman joins a sad list of Hollywood stars whose lives were seemingly cut short by drugs, here is a look at other losses.
A look at the life and career of Philip Seymour Hoffman who has died from an "apparent drug overdose" aged 46.