A post-mortem examination will be carried out on the body of Philip Seymour Hoffman today, CNN reported, citing a New York City spokeswoman.
Police were combing his New York apartment for evidence yesterday, the report said, working on the assumption that the actor died of a heroin overdose.
A variation 100 time more potent than heroin - laced with the painkiller Fentanyl - is causing a spike in deaths on the US East Coast.
Philip Seymour Hoffman joins a sad list of Hollywood stars whose lives were seemingly cut short by drugs, here is a look at other losses.
A look at the life and career of Philip Seymour Hoffman who has died from an "apparent drug overdose" aged 46.