Prime Minister David Cameron said that Labour's win at the Wythenshawe and East Sale by-election was not "particularly surprising", but conceded that voters were sending a signal to the Conservative party, which came third in the vote, behind UKIP.
"Obviously one would prefer to come second rather than third, but I dont think this is a particularly surprsing result in Labour holding this seat," Mr Cameron told ITV's Daybreak.
"I don't think it was the sort of break through that people were talking about," he added.
"When people know that there's a by-election, they know the government isn't going to change, but obviously messages are sent, and signals are sent and protests are made, and governments should always listen to those things and I always do."
More top news
Frequent snowfall expected across much of the north this evening and strong northeasterly winds will make it feel noticeably cooler.
Tesco recalls own-brand squash after customers complain of "disgusting taste" and parents worry it may have caused children's stomach upset.
Bradford City co-chairman Mark Lawn has blasted TV broadcasters over their FA Cup fifth round match choices