Citizens Advice has said an extra room "can be a lifeline" for a disabled person, calling it "as vital as a guide dog or a wheelchair".
Chief executive Gillian Guy said for many people a spare room "is essential to their wellbeing" as it is needed for dialysis equipment or room for a carer.
Ms Guy said: "Many sick and disabled people have bedrooms which have been adapted to help them to cope with their condition.
"Moving disabled people out of their houses is not only a potential risk to their health, but can cost the individuals affected and councils significant amounts of money if they need to start from scratch in a new home."
More top news
Sir Bernard Hogan-Howe said a judge-led review into how the Met Police handled allegations of past sex abuse is "the right thing to do".
After his son took his own life, grieving father Dick Moore began campaigning for mental health awareness. Here, he shares his advice.
The 13-year-old died in hospital after being hit in the back of the head by a bullet when his cousin fell of a hoverboard.