Spoof X Factor musical I Can't Sing! is to close on May 10, just six weeks and three days after opening. The show, written by comic Harry Hill, opened on March 26 in London's West End.
Preview performances were postponed twice in a week with producers citing technical problems.
Rebecca Quigley, chief executive of Stage Entertainment UK, said: "We are sad to be bringing I Can't Sing! to a close but are immensely proud to have co-produced the show [...] The West End can be an unpredictable place as the closure of a number of high profile productions recently has shown.
"I Can't Sing! has had audiences on their feet night after night, four and five-star reviews from the critics and an amazing company and creative team, but it seems that isn't always enough."
People who have already bought tickets for performances due to be held after May 10 were urged to contact their original point of purchase.