Barclays will cut 7,000 jobs from its investment banking division by 2016 as part of a strategy review.
The bank has already announced job losses around the group of 12,000 for this year, but this has been increased to 14,000.
It comes two days after Barclays announced that first quarter earnings from the division fell by half, meaning profits at the group slid by 5%. In a statement, Barclays said:
Plans for the Investment Bank will result in gross headcount reductions of around 7,000 by 2016 across core and non-core.
The overall 2014 Group gross headcount reduction has been increased to 14,000.
More top news
Former Girls Aloud singer Kimberley Walsh is pregnant with her second child, she has revealed.
Chancellor George Osborne will seek to reassure financial markets on Monday morning following Britain's decision to leave the EU.
In his first outing since the referendum result, the lead Leave campaigner has outlined his vision for a post-Brexit Britain.