Fire crews have blasted the flames with a water jet while flames could be seen through the scorched windows and billowing out of the roof of Glasgow School of Art's (GSA) Charles Rennie Mackintosh building.
The Scottish Fire and Rescue Service have sent several appliances from Cowcaddens, Yorkhill and Maryhill fire stations to the fire at the famous sandstone building.
More top news
One of the greatest sporting events on earth gets underway this week as the Ryder Cup heads to Scotland, here's everything you need to know
A toddler was in need of an unusual rescue after she got a kettle stuck on her head while playing at home in Chile.
British Defence Secretary Michael Fallon is in the Middle East to gather support for the international military campaign against IS.