A Lib Dem spokesman said:
This is a disappointing night and a bad result for the party but we knew that this election would be difficult.
The Liberal Democrats fought a strong campaign driven by our values as a party that at its core is unashamedly pro-European. It was always going to be difficult trying to overcome so many decades of anti-European sentiment but we do not regret it and remain proud of our principles.
Voters across Europe have sent a strong anti-EU message and where other parties have sought to exploit people's fears, we have continued to make a positive case for the importance of staying in the EU.
We know that our party's activists have worked tirelessly to get the message across on the doorstep and it is always hard to see so many hardworking Liberal Democrat MEPs lose their seats despite years of dedicated service in the European Parliament.
The general election will be fought on our record in Government and these results do not change the fact that we've delivered an economic recovery, cut income tax for 24 million people, helped business create 1.6 million jobs and made more apprenticeships possible than ever.
Today EU leaders voted to back Jean-Claude Juncker as new president of the very powerful EU commission, which looks like business as usual.
In Essex the potential damage Ukip could do to Miliband's Downing Street elections is clear. He is there listening to voter's concerns.
The EU parliament is about to welcome the most Eurosceptic and right-wing intake in its history.