Pope Francis told the Israeli and Palestinian presidents that they "must respond" to their people's yearning for peace in the Middle East and find "the strength to persevere in undaunted dialogue".
The pope made his appeal to Shimon Peres and Mahmoud Abbas at the end of an unprecedented prayer meeting among Jews, Christians and Muslims in the Vatican gardens that marked the first time the two presidents have met in public in more than a year.
More top news
Questions on Russia and Syria are sure to dominate Defence Secretary Michael Fallon's meeting with his US counterpart Ash Carter.
Smoking could kill two million Chinese in 2030 with the country facing a "growing epidemic of premature death from tobacco".
A great-great-great-grandmother has become an unlikely star at the age of 93 after her grandson shared a video of her dancing to rap music.